Malena Manzi Ph.D.
ORCID ID: 0000-0002-1709-0685
Curriculum vitae
Education
- 2001-2003: High School with Natural Science orientation - Buenos Aires, Argentina
- 2004-2010: Biochemistry degree - University of Buenos Aires, Faculty of Pharmacy and Biochemistry (Argentina)
- 2010-2011: Research initiation project - University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Department of Biological Chemistry - Field of study: Cell Biology and Biochemistry. Project title: “Study of Galectin-1 expression in endothelial cells and its role in hepatocytes adhesion”
- 2011-2016: Ph.D. degree - University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Department of Biological Chemistry - National Scientific and Technical Research Council (CONICET) (Argentina). Field of study: Cell Biology and Biochemistry. Ph.D thesis “Galectin-1 relevance in hepatocellular carcinoma development and progression. Its role as a link between tumor hepatocytes and sinusoidal endothelial cells”.
Current position
- Postdoc at University of Pardubice.
Previous positions
- 2020-2022: Researcher staff of CONICET at the National Institute of Industrial Technology (INTI), Argentina. Project: Development of analytical methods applying LC-MS for the characterization and pharmacometabolomic studies of new potential antitumor drugs. Supervisor: María Eugenia Monge Ph.D., María Julieta Comin Ph.D.
- 2016-2019: Postdoc Researcher at Centro de Investigaciones en Bionanociencias (CIBION-CONICET). Project: Untargeted metabolomic and lipidomic studies for cancer biomarker using LC-HR-MS. Supervisor: María Eugenia Monge, Ph.D.
Research Interests
- Clinical lipidomics applying mass spectrometry coupled with high-performance liquid chromatography (RP-UHPLC, HILIC, UHPSFC) focused on cancer biomarker discovery.
- Translation of lipidomic research to the clinical practice.
- Fluxomic studies to understand biological mechanisms involved in diseases.
Membership
- Member of the Scientific Committee of the Argentine Mass Spectrometry Congress organized by the Argentine Society of Mass Spectrometry (2022)
Research awards
- Best poster presentation award at the XXXV Multidisciplinary Oncology Conference organized by the Instituto de Oncología A. H. Roffo (Argentina, 2022).
- Best oral presentation award at the 4th International Mass Spectrometry School organized by the International Mass Spectrometry Foundation (Spain, 2019).
- Best Project in Human Cancer Research awarded by Florencio Fiorini Fundation, National Cancer Institute (Argentina, 2015).
Publications
- 11 esearch and review articles in international journals.
- Author and co- author of more than 40 presentations at international and national conferences.
- H-index 11.
Grant projects
- Principle Investigator. Project PICT 2021-00079 founded by Argentine National Agency for the Promotion of Research, Technological Development and Innovation. Title: Development of analytical methods for drug characterization applying mass spectrometry.
- Member of research teams. 11 projects founded by Argentine National Agency for the Promotion of Research, Technological Development and Innovation, National Scientific and Technical Research Council and University of Buenos Aires.
Teaching
- 2020-2023. Assistant Professor. University of Buenos Aires, Faculty of Natural Science, Department of Physiology, Cellular and Molecular Biology. Area: Biotechnology. Discipline: Genetics.
- 2021-2022. Lecturer at post-graduate course “Metabolic control analysis: study and design of biological systems”. Topic: “Metabolomics. Concepts and tools for metabolic pathways analysis”. University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Department of Biological Chemistry.
- 2020-2021. Teaching Assistant . University of Buenos Aires. Discipline: Chemistry.
- 2013-2020. Teaching Assistant. University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Department of Biological Chemistry. Discipline: Advanced Biological Chemistry.
- 2013. Laboratory Teaching Assistant. University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Department of Biological Chemistry. Master in Biotechnology. Discipline: Purification of recombinant proteins.
- 2009-2013. Laboratory Teaching Assistant. University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Department of Biological Chemistry. Discipline: Advanced Biological Chemistry.
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