News

Article "LipidQuant 1.0: automated data processing in lipid class separation - mass spectrometry quantitative workflows" just published in Bioinformatics.

Article "Quality control requirements for the correct annotation of lipidomics data" published in Nature Communications

Preprints of our latest manuscripts in peer-review process

• Lipidomic profiling of human serum enables detection of pancreatic cancer posted on medRxiv on January 26, 2021, 2. revision under consideration in Nat. Com.

Nabídka doktorských, diplomových a bakalářských prací

• Baví vás analytická chemie a jde Vám dobře práce v analytických laboratořích?
• Máte chuť něco dokázat?
• Chcete se podílet na zajímavém výzkumu při vývoji včasné diagnostiky pro nádorová onemocnění?
• Chcete pracovat v mladém kolektivu, kde kromě práce je řada dalších mimopracovních aktivit?
• Domluvíte se aspoň na základní úrovni anglicky?

Pokud ano, tak výborně, to jste na správném místě. Pokud Vás zaujmou témata vypsaných studentských prací, tak se přijďte za námi podívat, rádi Vám ukážeme laboratoře a probereme, co Vás bude zajímat.

Pozvánka pro studenty - přidej se k nám!

Call for students

• Are you interested in some exciting research in the area of lipid cancer biomarkers?
• Do you want to do PhD in the field of analytical chemistry?
• Are you familiar with chromatography and mass spectrometry, at least at basic level?

Great, you may be interested in Ph.D. study in our group. Please look at our topics and write me, if you are interested.

Or you already have your Ph.D. degree in analytical chemistry or biochemistry, and you are looking for postdoc stay. Then you can send me your CV and motivation letter, and I will check our possibilities for the most interesting applications.

Welcome for students - join to us!

KEY RECENTLY PUBLISHED PAPERS AND PATENTS

• J. Lipid Res. (2021) in press. Recommendations for Good Practice in Mass Spectrometry-Based Lipidomics
• Bioinformatics (2021) in press. LipidQuant 1.0: automated data processing in lipid class separation–mass spectrometry quantitative workflows
• Anal. Chem. 93 (2021) 13835. Simple and Reproducible Derivatization with Benzoyl Chloride: Improvement of Sensitivity for Multiple Lipid Classes in RP-UHPLC/MS
• Scientific Reports 11 (2021) 20322. Plasma Lipidomic Profiles of Kidney, Breast, and Prostate Cancer Patients Differ from Healthy Controls
• Nat. Com. 12 (2021) 4771. Quality control requirements for the correct annotation of lipidomics data
• Anal. Bioanal. Chem. (2021) in press. Retention dependences support highly confident identification of lipid species in human plasma by reversed-phase UHPLC/MS
• Talanta 231 (2021) 122367. Intra-laboratory cross-comparison of four lipidomic quantitation platforms using hydrophilic interaction liquid chromatography vs. supercritical fluid chromatography coupled to two quadrupole - time-of-flight mass spectrometers.
• Metabolites 11(3) (2021) 140. Structural Characterization of Glycosphingolipids in Human Plasma using Hydrophilic Interaction Liquid Chromatography – Electrospray Ionization Mass Spectrometry.
• Anal. Chim. Acta 1137 (2020) 74-84. Determination of one year stability of lipid plasma profile and comparison of blood collection tubes using UHPSFC/MS and HILIC-UHPLC/MS.
• Anal. Bioanal. Chem. 412 (2020) 2375-2388. Validation of lipidomic quantitative methods based on lipid class separation - mass spectrometry: Comparison of supercritical fluid chromatography and hydrophilic interaction liquid chromatography.
• Nat. Metab. 1 (2019) 745–747 Lipidomics need more standarization
• European patent EP 3514545 A method for diagnosing pancreatic cancer based on lipidomic analysis of a body fluid